Perfect Opposites is a romantic comedy about a young couple facing that momentous transition between college and adult life.
Drew (Martin Henderson), a charming soon-to-be law school graduate, falls in love with Julia (Piper Perabo), a studious college student, just two months before graduation.
Not wanting to part ways, Drew impulsively asks Julia to move with him to Los Angeles where he has a job lined up at a prestigious entertainment law firm.
Enamored, Julia agrees.
They quickly forge a friendship with their neighbors, Elyse and Lenny (Jennifer Tilly and Artie Lange), but trouble soon finds its way into the couple's lives.
Drew becomes infatuated with his new job - and the Hollywood scene it revolves around - and begins ignoring Julia, who has begun to notice her boyfriend's wandering eye and indifference toward her troubles in finding a job in LA.